By I Barry Holland,Susan P. C. Cole,Karl Kuchler, et al.Elsevier|Elsevier Science||Academic PressAdult NonfictionScienceLanguage(s): EnglishOn sale date: 13.10.2011Street date: 07.01.2003
ABC Proteins is an in-depth, updated research of all that's identified in regards to the topic so far. It discusses and compares evolution, biology and mechanism of motion of all identified ABC proteins, together with the 1st structural experiences in addition to medical implications. it will likely be necessary to an individual attempting to remain abreast of the newest findings. This ebook is bound to turn into a vintage and should usually be updated.
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Extra info for ABC Proteins. From Bacteria to Man
3B showing the different dispositions of the highly conserved but functionally different MDR1, MDR3 and BSEP proteins). The second important issue of this classification is that it does not reflect the universal classification of living organisms. The consequences of these issues will be discussed in the ‘Conclusions and Perspectives’ section at the end of the chapter. In the following sections, I shall discuss the known or predicted functions of the ABC systems found in each class. 8. 2 Typical organization of class 1 exporters.
Cole Karl Kuchler Christopher F. Higgins ABC TRANSPORTERS: AN INTRODUCTION AND OVERVIEW CHRISTOPHER F. HIGGINS and KENNETH J. LINTON INTRODUCTION ABC (ATP-binding cassette) transporters comprise one of the largest of all paralogous protein families. ABC transporters, as far as we know, are found in all cells of all species from the lowliest microbe to man. , Chapter 3). The diverse scientific backgrounds of the authors of this volume is one illustration of how ABC transporters play central roles in every kind of physiological system.
PART I PHYLOGENY AND EVOLUTION OF ABC TRANSPORTERS CHAPTER 1 PHYLOGENETIC AND FUNCTIONAL CLASSIFICATION OF ABC (ATP-BINDING CASSETTE) SYSTEMS* ELIE DASSA This paper is dedicated to the memory of Maurice Hofnung (1942–2001), a pioneer in the study of ABC (ATP-binding cassette) systems. Two decades ago, by noticing a strong sequence similarity between HisP and MalK, the two first-described ABC proteins, he initiated the studies that led to the identification and characterization of this large superfamily.
ABC Proteins. From Bacteria to Man by I Barry Holland,Susan P. C. Cole,Karl Kuchler, et al.Elsevier|Elsevier Science||Academic PressAdult NonfictionScienceLanguage(s): EnglishOn sale date: 13.10.2011Street date: 07.01.2003